Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in organic and confinement swine operations in Iowa and Illinois
2009 PPT Presentation at ASM ESCMID Conference in London, UK.
Published on: Mar 4, 2016
Transcripts - Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in organic and confinement swine operations in Iowa and Illinois
Prevalence of methicillin-resistant Staphylococcusaureus (MRSA) in organic and confinement swine operations in Iowa and Illinois Abby L. Harper, MPH University of Iowa Center for Emerging Infectious Diseases 10-09-2009
Introduction to MRSA Methicillin-resistant Staphylococcus aureus (MRSA) Gram positive bacterium Leading cause of hospital-associated infectionsImage: http://trouble.philadelphiaweekly.com/archives/MRSA220207_400x379%5B1%5D.jpg
Introduction to MRSA Not only a hospital problem anymoreReference: NEJM 2005;352:468-75NEJM 2008;358:11.Images: : http://www.foodpoisonblog.com/dog_cat.jpghttp://agebb.missouri.edu/commag/swine/pigs.jpghttp://www.smh.com.au/ffximage/2006/07/26/cattle26706_wideweb__470x313,0.jpg
MRSA and Swine First identified in the Netherlands, 2005 Pig farmers: higher rate of colonization with methicillin-susceptible S. aureus (MSSA) and MRSAReference: EID 2005;11:1965-66
MRSA and Swine Swine-associated MRSA also found in Denmark, Germany, Austria, France, Canada USA?
Swine MRSA in the USA? Iowa: #1 pork producing state in the USA 16 million hogs = 25% of hogs raised in the U.S. = $4 billion/yearImage: http://en.wikipedia.org/wiki/Iowa
Multi-state study 18 farms per investigator 24 animals tested per farm Nasal + pharyngeal sampling, humans 17 farms tested
Summary – Results in Swine No MRSA found to date on organic farms in Iowa Overall prevalence, swine: 45/408 (11%) Confinement swine: 45/192 (24%)
Summary – Results in Humans Humans: 27/86 (31.4%) Humans working in confinement: 27/61 (44.3%) Confirmed as ST398; first identification in US
Confinements as amplifiersand reservoirs 1000s of animals in small space Ventilation systems Low-tech environmental sampling All but 1 grew MRSA Map created by: Abby L. Harper Sources: Abby Harper Iowa Geologic Survey – DNR
Follow-up Environmental Sampling PhD student in Industrial Hygiene Anderson impact sampler CFUs / volume of air May indicate MRSA particle sizeSource: http://www.teagasc.ie/research/reports/dairyproduction/3989/eopr-3989.asphttp://www.pacwill.ca/en/ProductsServices/6stage.htm
Summary MRSA is present in U.S. swine and swine workers in confinement facilities Potential to spread to larger community Reservoir of resistanceImage: http://cuteoverload.com/2009/04/27/pucker-up-behbeh/
Future directions More general study of MRSA in rural Iowa Population prevalence & strain types Animals other than swine Role of antibiotics?
Co-authors and team members Tara Smith (PI) Mike Male, Anne Dressler,Blake Hanson, Shylo Wardyn (MS students) Jennifer Kroeger (PhD student) Phil Scheibel (undergraduate) Loreen Herwaldt MD, Dan Diekema MD (UIHC) http://www.public-health.uiowa.edu/CEID/ firstname.lastname@example.org