Natalizumab DMF (Tecfidera)
Option 1: Immediate switch (no wash‐out)
Natalizumab
DMF (Tecfidera)
Option 2: Three month ove...
of 1

Natalizumab to DMF switching

trial design
Published on: Mar 3, 2016
Published in: Government & Nonprofit      
Source: www.slideshare.net


Transcripts - Natalizumab to DMF switching

  • 1. Natalizumab DMF (Tecfidera) Option 1: Immediate switch (no wash‐out) Natalizumab DMF (Tecfidera) Option 2: Three month overlap M3 M4 M5 M6M0M‐1M‐2M‐3M‐4M‐5…… M‐6 3 month overlap VS. Hypothesis: A 3‐month overlap of DMF with natalizumab treatment will prevent rebound MRI  activity post‐natalizumab compared to no overlap of the treatments. 1° outcome: no. of Gd‐ enhancing lesions from M3‐M6 How bold is Biogen‐Idec?

Related Documents