“New tools for extraction, purification and
detection based on intelligent polymers“
POLYMERS DESIGNER
Be Selective
www.po...
Founded in 2004, POLYINTELL develops and
manufactures new products for sample
preparation, selective extraction and detect...
•Molecularly Imprinted
Polymers (MIP)
•Intelligent Polymers
•3 specialized teams:
 Organic chemistry
 Polymer chemistry
...
FACILITIES & EQUIPMENT
• Located at Pharma Parc II, Val de Reuil , 90km from
Paris - FRANCE
• 600m2 including fully equipp...
TECHNOLOGY
Self-assembly Polymerization Target
extraction
BENEFITS
•High affinity and selectivity
•Robust and stable mater...
From material to products
AFFINIMIP®SPE
Crushed monoliths
Meso-, macro-porous : from 2nm to 200nm
Micropores < 2nm
Microsc...
AFFINIMIP® Selective Extraction Cartridges
For sample preparation
Loading Washing steps
Analyte elution
High recovery and ...
Applications of AFFINIMIP ® SPE
Coming soon :
•AFFINIMIP® Phenolic compounds
•AFFINIMIP® Estradiol
Mycotoxins:
• AFFINIMIP...
AFFINIMIP® Zearalenone
AFFINIMIP® Zearalenone selective extraction cartridges
•Perfect clean-up for trace analysis of ZON ...
AFFINIMIP® Ochratoxin A
AFFINIMIP® Ochratoxin A selective extraction cartridges
•Perfect clean-up for trace analysis of OT...
AFFINIMIP® Patulin New!
AFFINIMIP® Patulin selective extraction cartridges
•Simple sample preparation
•Perfect clean-up sy...
Custom-made product
Customers: Sanofi-Aventis, Servier,
GSK, Roche, Pfizer, …
BE SELECTIVE
www.polyintell.com
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Polyintell

Published on: Mar 4, 2016
Source: www.slideshare.net


Transcripts - Polyintell

  • 1. “New tools for extraction, purification and detection based on intelligent polymers“ POLYMERS DESIGNER Be Selective www.polyintell.com
  • 2. Founded in 2004, POLYINTELL develops and manufactures new products for sample preparation, selective extraction and detection of specific target analytes. Offers •Catalog products •Custom-made products Application fields • Food safety • Diagnostic •Pharmaceutical R&D COMPANY PROFILE
  • 3. •Molecularly Imprinted Polymers (MIP) •Intelligent Polymers •3 specialized teams:  Organic chemistry  Polymer chemistry  Analytical chemistry • Patent portfolio : 6 patents STRONG IN HOUSE KNOW-HOW
  • 4. FACILITIES & EQUIPMENT • Located at Pharma Parc II, Val de Reuil , 90km from Paris - FRANCE • 600m2 including fully equipped laboratories • On site production unit
  • 5. TECHNOLOGY Self-assembly Polymerization Target extraction BENEFITS •High affinity and selectivity •Robust and stable materials •Fast development &cost effective New Molecular Recognition Phase Based on Molecularly Imprinted Polymers Molecular Recognition Materials
  • 6. From material to products AFFINIMIP®SPE Crushed monoliths Meso-, macro-porous : from 2nm to 200nm Micropores < 2nm Microscopic image Particles size : • 30 -80 µm • 50-60 µm • 8-10 µm Porous micro-beads
  • 7. AFFINIMIP® Selective Extraction Cartridges For sample preparation Loading Washing steps Analyte elution High recovery and selectivity! Catalog products : AFFINIMIP®
  • 8. Applications of AFFINIMIP ® SPE Coming soon : •AFFINIMIP® Phenolic compounds •AFFINIMIP® Estradiol Mycotoxins: • AFFINIMIP® Zearalenone • AFFINIMIP® Ochratoxin A •AFFINIMIP® Patulin (New !) Food safety Diagnostics Pharma R&D • AFFINIMIP® Catecholamine •AFFINIMIP® Metanephrine • AFFINIMIP® Tamoxifen •AFFINIMIP® GSH
  • 9. AFFINIMIP® Zearalenone AFFINIMIP® Zearalenone selective extraction cartridges •Perfect clean-up for trace analysis of ZON from maize and wheat Application Chromatograms of maize sample spiked with zearalenone at level of 85 μg.Kg-1 before clean-up and after extraction through AFFINIMIP® SPE. Zearalenone Column Hypersil Gold 150 x 2.1 mm, 0.2 mL/min, Vinj = 10 µL, lex =275 nm - lem=450 nm, 60-40 MeOH-H2O
  • 10. AFFINIMIP® Ochratoxin A AFFINIMIP® Ochratoxin A selective extraction cartridges •Perfect clean-up for trace analysis of OTA from maize and wheat Application : selective extraction of Ochratoxin A from wheat Ochratoxin A —— AFFINIMIP® SPE —— Before clean-up Column Hypersil Gold 150 x 2.1 mm, 0.2 mL/min, Vinj = 10 µL, lex =333 nm - lem=460 nm, 60-40 MeOH-H2O (1%AA) Minutes 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 8 9 10 11 12 13 14 15 16 17 8 9 10 11 12 13 14 15 16 17 2.5 µg/kg
  • 11. AFFINIMIP® Patulin New! AFFINIMIP® Patulin selective extraction cartridges •Simple sample preparation •Perfect clean-up system for trace analysis of Patulin •Applicable to several apple derived matrices Application : selective extraction of Patulin Patulin —— AFFINIMIP® SPE —— Before clean-up 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 mAU 0 10 20 30 40 50 60 70 80 90 100 110 mAU 0 10 20 30 40 50 60 70 80 90 100 110 High recovery and selectivity!
  • 12. Custom-made product Customers: Sanofi-Aventis, Servier, GSK, Roche, Pfizer, …
  • 13. BE SELECTIVE www.polyintell.com

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