PREVENTATIVE HEARTWORM
PRODUCTS IN DOGS & CATS
Kathy Chow
PharmD Candidate 2014
Western University of Health Sciences
Vete...
OUTLINE
 Prevalence
 Cycle of heartworm
 Location
 Clinical signs
 Diagnosis
 Heartworm in cats
 Heartworm preventa...
HOW PREVALENT IS HEARTWORM DISEASE?
www.veterinarypracticenews.com
CYCLE OF HEARTWORM
HOW DOES HEARTWORM CAUSE DAMAGE IN
THE HEART?
CLINICAL SIGNS IN DOGS?
 History
 Physical Exam
 Clinical Signs
Mild
Asymptomatic or cough
Moderate Cough, exercise int...
CLINICAL SIGNS IN DOGS?
Severe Cough, exercise intolerance, dyspnea,
abnormal heart and lung sounds, enlarged
liver (hepat...
DIAGNOSIS OF HEARTWORM DISEASE
 ELISA
 Preferred method
 Microfilaria Testing
 Radiography
 ECHO
 ECG
CATS AND HEARTWORM
 Prevalence
 typically 5% to 20% of that in dogs
 Life cycle
 Shorter (2-3 years)
 Clinical Signs
...
HEARTWORM PREVENTATIVE PRODUCTS
Product;
Species;
Rx/OTC
Active
Ingredients
; route of
administra
tion
PreventHeart
worm
H...
Product;
Species;
Rx/OTC
Active
Ingredients
; route of
administrat
ion
PreventHeart
worm
Hookworm
Roundworm
Whipworm
Tapew...
HEARTWORM PREVENTATIVE PRODUCTS
Product;
Species;
Rx/OTC
Active
Ingredients;
route of
administratio
n
PreventHeart
worm
Ho...
HEARTWORM PREVENTATIVE PRODUCTS
Product;
Species;
Rx/OTC
Active
Ingredients
; route of
administrat
ion
PreventHeart
worm
H...
Product;
Species;
Rx/OTC
Active
Ingredients
; route of
administrat
ion
PreventHeart
worm
Hookworm
Roundworm
Whipworm
Tapew...
HEARTWORM PREVENTATIVE PRODUCTS
Product;
Species;
Rx/OTC
Active
Ingredients
; route of
administra
tion
PreventHeart
worm
H...
CAUTION IN CERTAIN BREEDS
 MDR1 Gene Mutation
 Australian Shepherd
 Australian Shepherd Mini
 Border Collie
 Collie
...
QUESTIONS?
REFERENCES
 Heartworm Society. Current Canine Guidelines.
http://www.heartwormsociety.org/veterinary-resources/canine-gui...
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Prevantative Heartworm Products in Dogs & Cats

Published on: Mar 4, 2016
Source: www.slideshare.net


Transcripts - Prevantative Heartworm Products in Dogs & Cats

  • 1. PREVENTATIVE HEARTWORM PRODUCTS IN DOGS & CATS Kathy Chow PharmD Candidate 2014 Western University of Health Sciences Veterinary Specialty Hospital November 6, 2013
  • 2. OUTLINE  Prevalence  Cycle of heartworm  Location  Clinical signs  Diagnosis  Heartworm in cats  Heartworm preventative products  MDR1 Gene mutation
  • 3. HOW PREVALENT IS HEARTWORM DISEASE? www.veterinarypracticenews.com
  • 4. CYCLE OF HEARTWORM
  • 5. HOW DOES HEARTWORM CAUSE DAMAGE IN THE HEART?
  • 6. CLINICAL SIGNS IN DOGS?  History  Physical Exam  Clinical Signs Mild Asymptomatic or cough Moderate Cough, exercise intolerance, abnormal lung sounds
  • 7. CLINICAL SIGNS IN DOGS? Severe Cough, exercise intolerance, dyspnea, abnormal heart and lung sounds, enlarged liver (hepatomegaly), syncope (temporary loss of consciousness from reduced blood flow to the brain, ascites (fluid accumulation in the abdominal cavity), death Caval Syndrome Sudden onset of severe lethargy and weakness accompanied by hemoglobinuria (high hemoglobin)
  • 8. DIAGNOSIS OF HEARTWORM DISEASE  ELISA  Preferred method  Microfilaria Testing  Radiography  ECHO  ECG
  • 9. CATS AND HEARTWORM  Prevalence  typically 5% to 20% of that in dogs  Life cycle  Shorter (2-3 years)  Clinical Signs  Diagnostic  ECHO
  • 10. HEARTWORM PREVENTATIVE PRODUCTS Product; Species; Rx/OTC Active Ingredients ; route of administra tion PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often Iverhart Plus For dogs Rx Ivermectin ; Pyrantel Pamoate Oral X X X >6 weeks and no weight requireme nts Monthly Heartgard Plus For dogs Rx Ivermectin ; Pyrantel Pamoate Oral X X X >6 weeks and no weight requireme nts; Monthly
  • 11. Product; Species; Rx/OTC Active Ingredients ; route of administrat ion PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often Heartgard For cats Rx Ivermectin Oral X X >6 weeks and no weight requireme nts Monthly Iverhart Max For Dogs Rx Ivermectin; Pyrantel Pamoate; Praziquant el Oral X X X X >8 weeks and at least 6lbs Monthly HEARTWORM PREVENTATIVE PRODUCTS
  • 12. HEARTWORM PREVENTATIVE PRODUCTS Product; Species; Rx/OTC Active Ingredients; route of administratio n PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often Sentinel For Dogs Rx Milbemycin Oxime; Lufenuron Oral X X X X X >4 weeks and at least 2 lbs Monthly Advantage Multi For dogs Rx Moxidectin; Imidacloprid Topical X X X X X X 7 weeks of age or older and weighing at least 3 lbs Monthly
  • 13. HEARTWORM PREVENTATIVE PRODUCTS Product; Species; Rx/OTC Active Ingredients ; route of administrat ion PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often Advantage Multi For cats Rx Imidaclopri d; Moxidectin Topical X X X X X 9 weeks of age or older and weighing at least 2 lbs Monthly Revolution For Dogs Rx Selemectin Topical X X X 6 weeks of age or older and no weight requireme nt Monthly
  • 14. Product; Species; Rx/OTC Active Ingredients ; route of administrat ion PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often Revolutio n For Cats Rx Selemectin Topical X X X X X 8 weeks of age or older and no weight requireme nt Monthly Trifexis For Dogs Rx Milbemycin Oxime; Spinosad Oral X X X X X 8 weeks of age and older and weighing at least 5 lbs Monthly HEARTWORM PREVENTATIVE PRODUCTS
  • 15. HEARTWORM PREVENTATIVE PRODUCTS Product; Species; Rx/OTC Active Ingredients ; route of administra tion PreventHeart worm Hookworm Roundworm Whipworm Tapeworm Fleas FleaEggs Youngest age to start How often ProHeart 6 For Dogs Rx Moxidectin SQ Injection X X 6 months to 7 yo Every 6 months
  • 16. CAUTION IN CERTAIN BREEDS  MDR1 Gene Mutation  Australian Shepherd  Australian Shepherd Mini  Border Collie  Collie  English Shepherd  German Shepherd  McNab Sheepdog  Old English Sheepdog  Shetland Sheepdog  Mix breeds with any of the above
  • 17. QUESTIONS?
  • 18. REFERENCES  Heartworm Society. Current Canine Guidelines. http://www.heartwormsociety.org/veterinary-resources/canine-guidelines.html. Accessed November 3, 2013.  FDA. Prevent Heartworm in Pets Year-round. http://www.fda.gov/ForConsumers/ConsumerUpdates. Accessed November 2, 2013.  Canine and Feline Dirofilariasis. www.vetlearn.com. Accessed November 1, 2013  Canine and Feline Dirofilariasis, life cycle pathophysiology, and diagnosis. www.vetlearn.com. Accessed November 1, 2013.  Canine and Feline Dirofilariasis:  Prophylaxis,Treatment, and  Complications of Treatment. www.vetlearn.com. Accessed November 1, 2013.  Merck Veterinary Manual. Macrolytic Lactones. http://www.merckmanuals.com/vet/pharmacology/anthelmintics/macrocyclic_lacton es.html. Accessed November 4, 2013.  HeartGard Plus dogs and cats. Package insert. Accessed November 4, 2013.  Sentinel Package Insert. http://sentinelpet.com Accessed November 4, 2013

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