Nanotechnology in Cancer
Therapy
Antonio Di Martino
What is it Cancer?
 Is one of the leading cause of death worldwide
 Is represented by an uncontrolled cells growth
 Inv...
Nanotechnology in Cancer Therapy
 Nanotechnology = manipulation of matter on atomic, molecular and supramolecular
scale
...
Nanoparticles
Nanoliposomes Polymerics NanoshellsQuantum Dots
Metallic nanoparticles
 More flexible
 Size
 Shape
 Stru...
Golden Nanoparticles (AuNPs)
Great chance in cancer therapy
Tunable properties
Easy to prepare
Surface modification
H...
AuNPs in Cancer Therapy : Applications
 Photothermal therapy
 Radiotherapy
 Angiogenesis Inhibition
Optical properties
...
Conclusions
 Cancer is a complex disease
 Different molecular pathway are involved
 Nanomedicine represents a new conce...
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Nanotechnology in cancer therapy

Nanotechnology, cancer therapy, drug delivery, nanomedicine
Published on: Mar 3, 2016
Published in: Science      
Source: www.slideshare.net


Transcripts - Nanotechnology in cancer therapy

  • 1. Nanotechnology in Cancer Therapy Antonio Di Martino
  • 2. What is it Cancer?  Is one of the leading cause of death worldwide  Is represented by an uncontrolled cells growth  Involve many physiological pathways Which are current cancer therapies?  Surgery  Radiotherapy  Chemotherapy High efficiency Low selectivity Low therapeutic Index
  • 3. Nanotechnology in Cancer Therapy  Nanotechnology = manipulation of matter on atomic, molecular and supramolecular scale Nanomedicine = application of nanotechnology in therapeutic and diagnostic Drug Delivery System
  • 4. Nanoparticles Nanoliposomes Polymerics NanoshellsQuantum Dots Metallic nanoparticles  More flexible  Size  Shape  Structure  Composition  Encapsulation
  • 5. Golden Nanoparticles (AuNPs) Great chance in cancer therapy Tunable properties Easy to prepare Surface modification High encapsulation efficiency Application of Nanotechnology in Drug Delivery
  • 6. AuNPs in Cancer Therapy : Applications  Photothermal therapy  Radiotherapy  Angiogenesis Inhibition Optical properties Absorption in NUV and NIR High accumulation Index Chemical modification of protein involved
  • 7. Conclusions  Cancer is a complex disease  Different molecular pathway are involved  Nanomedicine represents a new concept of therapy  Reduction of side effects  High specificity  Improve the quality of life  Still lack of knowledge about toxicity over time

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