Nanotechnology in Drug
Development
Submitted by
Sukanta Das
Msc. 1st sem.
Introduction
Nanotechnology can be define in a variety
of ways, but the one common component is
technology that deals with...
Nanotechnology
• Nanotechnology breakthrough research in
Pharmaceutical & Biopharmaceutical Industry.
• Nanotechnology, is...
Use of Nanotechnology
Nanotechnology has produced a variety
of nonmaterial's, including nano composites
use in building ma...
Drug Discovery and Development
• Validate specific targets
• Discover the right molecule (potential drug) to
interact with...
Drug Discovery and Development
• Success requires immense resources
The best scientist minds, highly sophisticated
technol...
Drug Development and Delivery
• The multi-disciplinary field of nanotechnology
is making small device, closer and closer t...
Drug Development and Delivery
• Drug filled nano-capsules, release their
biological compounds on contact with cancers
only...
Successful Therapy Combines
Drug Discovery and Delivery
9
Nanotech Components
10
Nanotechnology Collaboration
11
Targeted Drug Delivery
Drug Delivery Carriers
13
Drug Delivery
System
Liposome's
Niosomes
Ethosomes
Aquasome
TransfersomesDendrimers
Polymeric
Nanoparticles
Bilosomes
Carb...
Carbon Nanotube
Carbon nanotubes are adept at
entering the nuclei of cells and may
one day be used to deliver drugs
and v...
Polymeric Nanoparticles
In recent years, biodegradable
polymeric nanoparticles have
attracted considerable attention as
po...
Research Priorities
SOME SIGNIFICANT ACHIEVEMENTS OF
NANODEVICES
Development of one dose a day ciprofloxacin using
nanotechnology
Tumor targ...
Drug Delivery Technology Important to Pharma Industry
Drug delivery formulations involve low cost
researchcomparedthatfor...
Conclusion
The use of nanotechnology in medicine in
general and drug delivery in particular is
spreading rapidly. For quit...
THANKING YOU
21
of 21

nanotechnology in drug development.

Now a day nanotechnology is part of our various type of work or activity.
Published on: Mar 3, 2016
Published in: Education      
Source: www.slideshare.net


Transcripts - nanotechnology in drug development.

  • 1. Nanotechnology in Drug Development Submitted by Sukanta Das Msc. 1st sem.
  • 2. Introduction Nanotechnology can be define in a variety of ways, but the one common component is technology that deals with materials smaller than 100 nanometers. One definition states that nanotechnology is the art and science of manupulating matter at the nanoscale to create new and unique materials and products. How small is nanometer? Really, really small too small to see even with light microscope.
  • 3. Nanotechnology • Nanotechnology breakthrough research in Pharmaceutical & Biopharmaceutical Industry. • Nanotechnology, is a field of science and technology. The aim of nanotechnology is to control matter at the atomic and molecular level. 3
  • 4. Use of Nanotechnology Nanotechnology has produced a variety of nonmaterial's, including nano composites use in building materials, naocrystals used in solar panels at semiconductors. Nanoparticals are used in stain-repellent clothing and sunscreens, nanocatalysis in drug development. Nanotechnology will provide the next new wave of products, with promises of food that can adjust its colour, flavour and nutrient content.
  • 5. Drug Discovery and Development • Validate specific targets • Discover the right molecule (potential drug) to interact with the target chosen • Test the new compound in the lab and clinic for safety and efficacy and • Gain approval and get the new drug into the hand of doctors and patients. 5
  • 6. Drug Discovery and Development • Success requires immense resources The best scientist minds, highly sophisticated technology and complex project management. It is also takes persistence and sometimes luck. Ultimately the process of drug discovery brings hope and relief to millions of patients 6
  • 7. Drug Development and Delivery • The multi-disciplinary field of nanotechnology is making small device, closer and closer to reality. • Manipulate and organize matter on the nano- scale. 7
  • 8. Drug Development and Delivery • Drug filled nano-capsules, release their biological compounds on contact with cancers only. • Nanotechnology will be applied at all stages of drug development, from formulations for optimal delivery to diagnostic applications in clinical trials. 8
  • 9. Successful Therapy Combines Drug Discovery and Delivery 9
  • 10. Nanotech Components 10
  • 11. Nanotechnology Collaboration 11
  • 12. Targeted Drug Delivery
  • 13. Drug Delivery Carriers 13
  • 14. Drug Delivery System Liposome's Niosomes Ethosomes Aquasome TransfersomesDendrimers Polymeric Nanoparticles Bilosomes Carbon Nanotube 14
  • 15. Carbon Nanotube Carbon nanotubes are adept at entering the nuclei of cells and may one day be used to deliver drugs and vaccines. The modified nanotubes have so far only been used to ferry a small peptide into the nuclei of fibroblast cells.
  • 16. Polymeric Nanoparticles In recent years, biodegradable polymeric nanoparticles have attracted considerable attention as potential drug delivery devices in view of their applications in drug targeting to particular organs/tissues, as carriers of DNA in gene therapy, and in their ability to deliver proteins, peptides and genes.
  • 17. Research Priorities
  • 18. SOME SIGNIFICANT ACHIEVEMENTS OF NANODEVICES Development of one dose a day ciprofloxacin using nanotechnology Tumor targeted taxol delivery using nanoparticles in Phase 2 clinical trial stage Improved ophthalmic delivery formulation using smart hydrogel nanoparticles Oral insulin formulation using nanoparticles carriers. Liposomal based Amphotericin B formulation
  • 19. Drug Delivery Technology Important to Pharma Industry Drug delivery formulations involve low cost researchcomparedthatfordiscoveryofnewmolecule, Minimizing the drug use would significantly reduce the effective cost of drug which would give financial relieftothepatients.
  • 20. Conclusion The use of nanotechnology in medicine in general and drug delivery in particular is spreading rapidly. For quite some time past nanoparticles are being use in pharmaceutical industry to reduce toxicity and side effects of drugs. However it is also realized now that these drug carriers systems may appears to be risky to patient. Therefore further research is necessary. More over in feature collaborative programs are to launched as nanotechnology study is very costly which requires very qualified and trained scientist and modern instruments.
  • 21. THANKING YOU 21